The Use of Cu-Atsm Treatment to Identify Cellular Mechanisms of Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis.

Increased metal content in the TDP-43A315T transgenic mouse model of frontotemporal lobar degeneration and amyotrophic lateral sclerosis

TNT Dang, NKH Lim, A Grubman, QX Li, I Volitakis, AR White, PJ Crouch

2014-01-01

Disrupted metal homeostasis is a consistent feature of neurodegenerative disease in humans and is recapitulated in mouse models of..